Projects and Cores

To identify host and pathogen factors that are crucial in respiratory infections and are predictors of disease severity, the HPMI researchers will utilize a multi-disciplinary System Biology Platform supported by three scientific Cores in support of two Projects.

Identification of host and bacterial pathways that control tuberculosis pathogenesis in humans

Leads: Jeffery Cox, Michael Glickman, Thomas Hawn; Co-I: Thuong Nguyen, Nevan Krogan

Determine clinically relevant host-viral dependency networks for respiratory infections

Leads: Nevan Krogan, Melanie Ott; Co-I: Jeffery Cox, Jennifer Doudna and Jyoti Batra

Technology Core

Leads: Jennifer Doudna and Danielle Swaney; Co-I: Klim Verba and Nevan Krogan

Modeling Core

Lead: Trey Ideker; Co-I: Andrej Sali and Nevan Krogan

Bioinformatics Core

Lead: Andrej Sali; Co-I: Ignacia Echeverria

Projects and Cores